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Most of these diseases have a strong genetic component and the latest in genetic research is being applied to their study thanks to The Discovery Eye Foundation (DEF).
DEF is currently funding research lead by M. Cristina Kenney, M.D., Ph.D. to identify genes involved in Age-related Macular Degeneration and to investigate the ways specific genes affect the clinical outcome and response to treatment of individual patients. The hope is to be able to tailor specific treatments to those who will benefit most from a particular treatment.
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It is becoming more evident that many eye diseases have a genetic component to their development. - In 1997, the first genetic mutations to be associated with age-related macular degeneration (AMD) were reported. This identified gene was the ABCR gene, which codes for a retinal binding protein.
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